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. 2022 Mar 28;3(1):81–98. doi: 10.12336/biomatertransl.2022.01.008

Table 5. Clinical trials of various vascular grafts. This table aims to be representative rather than comprehensive.

Intervention/treatment Number of patients Condition/disease Years Trial ID/phase Testing status
Device: Synthetic vascular grafts 207 Peripheral arterial occlusive disease 2010-2013 NCT01113892/NA Completed
Device: HAVG graft implantation 40 End-stage renal disease
Kidney failure, chronic
2012-2016 NCT01744418/NA Active, not recruiting
Device: FUSION Vascular Graft 117 Peripheral arterial occlusive disease (PAOD) 2009-2013 NCT01601496/NA Terminated
Device: POSS-PCU vascular graft 30 Renal insufficiency 2021-2025 NCT02301312/NA Not yet recruiting
Combination Product: Tissue Engineered Vascular Grafts 4 Single ventricle cardiac anomaly 2009-2017 NCT01034007/Phase 1 Completed
Device: ProEndoTecc Vascular Graft 33 Peripheral arterial disease
Peripheral vascular disease
2010-2012 NCT01095237/NA Terminated
Device: ASC coated ePTFE vascular graft
Device: Propaten graft
60 Lower limb ischemia 2011-2022 NCT01305863/NA Active, not recruiting
Biological: natural human collagen arteriovenous graft for haemodialysis access 10 End stage renal disease 2021-2022 NCT04905511/Phase 1 Recruiting
Device: POSS-PCU vascular graft 30 Renal insufficiency 2021-2025 NCT02301312/NA Not yet recruiting
Procedure: Revascularisation using a BIOPROTEC graft 45 Peripheral artery disease 2018-2023 NCT04018846/NA Recruiting
Device: Expanded polytetrafluoroethylene graft
Device: Bovine carotid artery graft
10 End stage renal disease Haemolysis Arteriovenous graft 2015-2018 NCT03300024/NA Terminated (Funding ended)
Device: Expedial vascular access graft 172 End stage renal disease 2004-2006 NCT00131872/Phase 2 Terminated
Device: Covera vascular covered stent 100 Arteriovenous fistula 2020-2023 NCT04261686/NA Enrolling by invitation
Device: Endovascular revascularisation of peripheral arteries 150 Vascular diseases, peripheral 2021-2022 NCT04765566/NA Active, not recruiting
Device: InnAVasc arteriovenous graft surgical implant 26 Kidney failure, chronicRenal dialysis 2019-2021 NCT03645681/NA Active, not recruiting
Procedure: blood sampling procedurethe vascular prosthesis manufactured by electrospinning 120 Arterial occlusive disease 2014-2015 NCT02255188/NA Completed
Procedure: revascularisation
Device: Propaten®
Device: Crude PTFE
228 Ischemia lesions 2018-2023 NCT03430076/NA Recruiting
Device: Paclitaxel-eluting graft 20 Haemodialysis access failure 2018-2023 NCT04285073/NA Recruiting
Device: GORE PROPATEN vascular graft
Procedure: Disadvantaged autologous vein graft
31 Peripheral arterial occlusive disease 2007-2010 NCT00617279/Phase 4 Terminated (study terminated due to low enrolment)
Device: EvoCit
Device: EvoHep
38 Kidney diseases Haemodialysis complication End stage renal disease 2018-2019 NCT03887468/ Completed
Combination product: Tissue engineered vascular grafts 24 Cardiovascular diseases 2020-2025 NCT04467671/Phase 2 Recruiting

Note: The information is obtained from clinicaltrials.gov. NA: not available.