FIGURE 3.

Strategy for the treatment of infertile women with sperm‐immobilizing antibodies. ⁶⁵ It is important to assess the 50% sperm‐immobilization unit (SI₅₀) titers to select treatments for infertile women with sperm‐immobilizing antibodies. A strategy for the treatments of infertile women with sperm‐immobilizing antibodies is shown according to the undulation patterns of individual patient's SI₅₀ titers. Patients with sperm‐immobilizing antibodies are divided into three groups according to their follow‐up SI₅₀ titers; Group A: the patients with continuously high SI₅₀ titers (>10 units) are recommended to be treated by in vitro fertilization–embryo transfer (IVF‐ET). Group B: the patients have intermediate SI₅₀ titer patterns around 10, and Group C; the patients with continuously low SI₅₀ titers (<10 units) are recommended to be treated by repeated or ordinary intra‐uterine insemination (IUI). If they are not able to be conceived by several cycles of IUI, then the treatment by IVF‐ET should be considered