Table 2.
Association of baseline variables and PIM (≥1 high risk medication per Beers or STOPP criteria).
| Variable | Category | All patients | PIM | No PIM | POR | 95% CI | |
|---|---|---|---|---|---|---|---|
| N | 718 (100%) | 482 (61.3%) | 236 (38.7%) | ||||
| Age, years | 70-74 | 271 (37.7%) | 190 (39.4%) | 81 (34.3%) | Ref | — | — |
| 75-79 | 225 (31.3%) | 149 (30.9%) | 76 (32.2%) | 0.84 | 0.57 | 1.22 | |
| ≥80 | 222 (30.9%) | 143 (29.7%) | 79 (33.5%) | 0.77 | 0.53 | 1.13 | |
| Gendera | Male | 405 (56.4%) | 281 (58.5%) | 124 (52.5%) | Ref | — | — |
| Female | 311 (43.3%) | 183 (41.1%) | 128 (47.2%) | 0.78 | 0.57 | 1.07 | |
| Raceb | White | 628 (87.5%) | 427 (89.1%) | 201 (85.1%) | Ref | — | — |
| Black | 52 (7.2%) | 29 (6.1%) | 23 (9.8%) | 0.59 | 0.34 | 1.05 | |
| Others | 35 (4.9%) | 23 (4.8%) | 12 (5.1%) | 0.90 | 0.44 | 1.85 | |
| Educationa | <High school | 111 (15.5%) | 81 (16.9%) | 30 (12.7%) | Ref | — | — |
| High school | 244 (34.0%) | 169 (35.2%) | 75 (31.8%) | 0.84 | 0.51 | 1.38 | |
| College or above | 361 (50.3%) | 230 (47.9%) | 131 (55.5%) | 0.65 | 0.41 | 1.04 | |
| Incomea | ≤$50 000 | 371 (51.7%) | 259 (54.0%) | 112 (47.7%) | Ref | — | — |
| >50 000 | 190 (26.5%) | 119 (24.8%) | 71 (30.1%) | 0.73 | 0.50 | 1.05 | |
| Declined to answer | 155 (21.6%) | 102 (21.3%) | 53 (22.5%) | 0.83 | 0.56 | 1.24 | |
| Marital statusa | Single | 17 (2.4%) | 9 (1.9%) | 8 (3.4%) | Ref | — | — |
| Married/domestic partnership | 449 (62.5%) | 312 (65.0%) | 137 (58.1%) | 2.02 | 0.77 | 5.36 | |
| Separated/widowed/divorced | 250 (34.8%) | 159 (33.1%) | 91 (38.6%) | 1.55 | 0.58 | 4.17 | |
| Cancer type | Gastrointestinal | 246 (34.2%) | 162 (33.9%) | 84 (35.6%) | Ref | — | — |
| Genitourinary | 109 (15.2%) | 65 (13.5%) | 44 (18.6%) | 0.74 | 0.41 | 1.34 | |
| Gynecological | 43 (6.0%) | 28 (5.8%) | 15 (6.4%) | 0.76 | 0.48 | 1.21 | |
| Breast | 56 (7.8%) | 33 (6.9%) | 23 (9.7%) | 0.96 | 0.49 | 1.90 | |
| Lung | 180 (25.1%) | 135 (28.0%) | 45 (19.1%) | 1.55 | 1.01 | 2.37 | |
| Lymphoma | 46 (6.4%) | 34 (7.1%) | 12 (5.1%) | 1.46 | 0.72 | 2.97 | |
| Others | 38 (5.3%) | 21 (4.5%) | 17 (6.3%) | 0.95 | 0.46 | 1.96 | |
| KPS | 20-60 | 93 (13.0%) | 67 (13.9%) | 26 (11.1%) | Ref | — | — |
| 70-80 | 379 (52.8%) | 271 (56.3%) | 108 (46.0%) | 0.97 | 0.59 | 1.61 | |
| 90-100 | 244 (33.9%) | 143 (29.7%) | 101 (43.0%) | 0.55 | 0.33 | 0.92 | |
| Life expectancyc | ≤12 months | 238 (33.1%) | 176 (36.9%) | 62 (26.5%) | Ref | — | — |
| >12 months | 473 (66.0%) | 301 (63.1%) | 172 (73.5%) | 0.62 | 0.44 | 0.87 | |
Two patients had missing data.
Three had missing data.
Seven had missing data.
Abbreviations: CI, confidence interval; KPS, Karnofsky Performance Status; PIM, potentially inappropriate medications; POR, prevalence odds ratio; STOPP, Screening Tool of Older Person’s Prescriptions.
Bolded values are statistically significant.