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. 2022 Jul 5;11:e77898. doi: 10.7554/eLife.77898

Figure 7. IGV screenshots of two novel maternal germline differentially methylated regions (DMRs).

(a) Novel maternally methylated germline DMR overlapping with the promoter of the paternally expressed ACTL10 gene. (b) Novel maternally methylated germline DMR overlapping with the promoter of the SYCE1 gene, which demonstrates paternal expression bias from parent-of-origin (PofO) allele-specific expression (ASE) track. Highlighted box regions represent the DMRs. PofO ASE track is created using publicly available ASE data from Zink et al., 2018 (see Materials and methods). Positive vertical bars (upward) represent paternal expression and negative bars (downward) represent maternal expression. The range for all methylation tracks is 0–1.

Figure 7.

Figure 7—figure supplement 1. Novel germline maternally methylated differentially methylated region (DMR) in maternally expressed DDA1 gene.

Figure 7—figure supplement 1.

The range for all methylation tracks is 0–1. In parent-of-origin (PofO) ASE track, positive or upward bars represent paternal expression bias and negative or downward bars represent maternal expression bias.
Figure 7—figure supplement 2. Novel germline maternally methylated differentially methylated region (DMR) in paternally expressed AC024940.1 (OVOS2) gene.

Figure 7—figure supplement 2.

The range for all methylation tracks is 0–1. In parent-of-origin (PofO) ASE track, positive or upward bars represent paternal expression bias and negative or downward bars represent maternal expression bias.
Figure 7—figure supplement 3. Novel germline maternally methylated differentially methylated region (DMR) 149 kb away from isoform dependent expressed NAPRT gene.

Figure 7—figure supplement 3.

The range for all methylation tracks is 0–1. In parent-of-origin (PofO) ASE track, positive or upward bars represent paternal expression bias and negative or downward bars represent maternal expression bias.
Figure 7—figure supplement 4. Novel germline maternally methylated differentially methylated region (DMR) 745 kb away from maternally expressed NTM gene.

Figure 7—figure supplement 4.

The range for all methylation tracks is 0–1. In parent-of-origin (PofO) ASE track, positive or upward bars represent paternal expression bias and negative or downward bars represent maternal expression bias.