Table 1. Forty-two detected imprinted differentially methylated regions (DMRs) from nanopore data and confirmed using whole-genome bisulfite sequencing (WGBS) data.
DMRs are named after the nearest gene (EnsemblGene 103 GRCh38.p13).
| ID | DMR name | Origin | Type | Distance to nearest imprinted gene | % Individuals with partial methylation | % Tissues with partial methylation |
|---|---|---|---|---|---|---|
| 22 | AC024940.1 | Maternal | Germline | 0 | 15.9 | 3.8 |
| 35 | DDA1 | Maternal | Germline | 0 | 7.3 | 15.4 |
| 38 | ACTL10;NECAB3 | Maternal | Germline | 0 | 3.7 | 8.7 |
| 42 | SYCE1 | Maternal | Germline | 3.2 kb | 4 | 9.1 |
| 12 | FAM83H | Maternal | Germline | 149 kb | 48.8 | 12 |
| 20 | OPCML | Maternal | Germline | 744.1 kb | 45.1 | 25 |
| 19 | YBX2P1 | Maternal | Germline | >2 Mb | 3.7 | 7.7 |
| 26 | NALCN-AS1 | Maternal | Germline | >2 Mb | 30.5 | 10 |
| 28 | PTGDR | Maternal | Germline | >2 Mb | 8.4 | 3.4 |
| 32 | AATK | Maternal | Germline | >2 Mb | 23.2 | 9.1 |
| 34 | MIR7-3HG | Maternal | Germline | >2 Mb | 8.1 | 3.6 |
| 2 | AC007391.3 | Maternal | Germline | >2 Mb | 37.2 | 60.7 |
| 5 | C4orf50 | Maternal | Germline | >2 Mb | 14.5 | 22.2 |
| 7 | CPLANE1 | Maternal | Germline | >2 Mb | 2.3 | 7.1 |
| 14 | SPTLC1 | Maternal | Germline | >2 Mb | 5.8 | 48.1 |
| 1 | BMP8A | Maternal | Somatic | 0 | 4.5 | 26.1 |
| 24 | LPAR6;RB1 | Maternal | Somatic | 0 | 2.3 | 10.3 |
| 36 | ZNF714 | Maternal | Somatic | 0 | 43.9 | 29.6 |
| 17 | BTBD7P1 | Maternal | Somatic | >2 Mb | 73.5 | 55.6 |
| 18 | ANKRD2 | Maternal | Somatic | >2 Mb | 34.1 | 3.8 |
| 23 | GJA3 | Maternal | Somatic | >2 Mb | 25.6 | 21.4 |
| 27 | RANBP20P | Maternal | Somatic | >2 Mb | 28 | 32 |
| 33 | NFE2L3P1 | Maternal | Somatic | >2 Mb | 29.3 | 44.4 |
| 39 | AL096828.3 | Maternal | Somatic | >2 Mb | 50 | 7.7 |
| 41 | SLC5A1 | Maternal | Somatic | >2 Mb | 56.1 | 25.9 |
| 8 | TMEM232 | Maternal | Somatic | >2 Mb | 25.6 | 37.9 |
| 9 | NME5 | Maternal | Somatic | >2 Mb | 22.1 | 10.7 |
| 11 | AC092634.8 | Maternal | Somatic | >2 Mb | 6.1 | 3.8 |
| 13 | CDRT15P6 | Maternal | Somatic | >2 Mb | 12.7 | 5.6 |
| 15 | TMOD1 | Maternal | Somatic | >2 Mb | 35.4 | 14.8 |
| 16 | LHX6 | Maternal | Somatic | >2 Mb | 44.6 | 25 |
| 30 | MIR6085 | Paternal | Germline | >2 Mb | 27.1 | 25.9 |
| 3 | PAX8;PAX8-AS1 | Paternal | Somatic | 0 | 24.4 | 32.1 |
| 4 | ZDBF2 | Paternal | Somatic | 0 | 53.6 | 58.6 |
| 29 | SNHG14 | Paternal | Somatic | 3 kb | 4.7 | 37.9 |
| 37 | AC092296.3 | Paternal | Somatic | 90 kb | 1.2 | 7.7 |
| 40 | RIMBP3 | Paternal | Somatic | 296 kb | 17.4 | 11.1 |
| 10 | RNU6-293P | Paternal | Somatic | 1.03 Mb | 65.1 | 37 |
| 21 | PARP11 | Paternal | Somatic | >2 Mb | 10.8 | 22.2 |
| 25 | UBAC2 | Paternal | Somatic | >2 Mb | 1.2 | 6.9 |
| 31 | CFAP161 | Paternal | Somatic | >2 Mb | 22.4 | 6.9 |
| 6 | MIR4456 | Paternal | Somatic | >2 Mb | 11.3 | 22.2 |