Table 2.
Marker levels of oxidative stress in patients with brain infarcts and coronary occlusions.
| CON n = 61 |
MCI+OVCO n = 59 |
MCI+TVCO n = 57 |
MCI+MVCO n = 54 |
|
|---|---|---|---|---|
| MDA (nmol/L) | 1.5 ± 0.2 | 2.1 ± 0.4∗ | 2.9 ± 0.6∗∗ | 3.7 ± 0.7∗∗∗ |
| ROS (MFI) | 24.6 ± 3.7 | 35.8 ± 7.8∗ | 46.3 ± 9.4∗∗ | 64.0 ± 12.1∗∗∗ |
| TBARS (μmol/L) | 2.9 ± 0.4 | 3.7 ± 0.7∗ | 4.9 ± 0.9∗∗ | 6.0 ± 1.3∗∗∗ |
| AOPP (μmol/L) | 0.9 ± 0.1 | 1.9 ± 0.3∗ | 2.7 ± 0.5∗∗ | 4.1 ± 0.8∗∗∗ |
| SOD 1 (ng/mL) | 25.4 ± 4.1 | 15.3 ± 2.9∗ | 10.0 ± 2.1∗∗ | 2.8 ± 1.3∗∗∗ |
| SOD 2 (ng/mL) | 32.7 ± 5.3 | 23.0 ± 3.5∗ | 9.2 ± 2.0∗∗ | 2.6 ± 1.4∗∗∗ |
| SOD 3 (ng/mL) | 38.2 ± 6.5 | 27.1 ± 4.2∗ | 9.3 ± 3.5∗∗ | 2.7 ± 0.7∗∗∗ |
| PON 1 (U/L) | 151.0 ± 29.5 | 140.0 ± 27.5∗ | 126.1 ± 25.4∗∗ | 115.8 ± 23.0∗∗∗ |
∗ P < 0.001 (CON group/MCI+OVCO group). ∗∗P < 0.001 (MCI+OVCO group/MCI+TVCO group). ∗∗∗P < 0.001 (MCI+TVCO group/MCI+MVCO group). Group comparisons (CON group/MCI+OVCO group/MCI+TVCO group/MCI+MVCO group) were made using ANOVA, P < 0.001. MCI: multiple cerebral infarcts; OVCO: one-vessel coronary occlusion; TVCO: two-vessel coronary occlusion; MVCO: multiple-vessel coronary occlusion; MDA: malondialdehyde; ROS: reactive oxygen species; TBARS: thiobarbituric acid reactive substance; AOPP: advanced oxidation protein products; SOD 1: superoxide dismutase 1; SOD 2: superoxide dismutase 2; SOD 3: superoxide dismutase 3; PON 1: paraoxonase 1.