Figure 6.

Correlative proinflammatory protein CXCR4 and neuronal marker protein c-fos of the spinal cord in rats with DNP was inhibited, and astrocytic marker protein GFAP was activated by intraperitoneal AMD3100 at 2 weeks and by daily oral NAC treatment at 5 weeks of diabetes. (a, e) Western blot demonstrated the protein expression of c-fos, GFAP, and CXCR4. (b–d, f–h) Quantitative analysis of c-fos, GFAP, and CXCR4 comparing with β-tubulin in spinal dorsal at 2 weeks and 5 weeks. In addition, all the obtained data can be shown to be means ± SD. ∗P < 0.05, n = 6/group.