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. 2022 Jun 28;2022:8547563. doi: 10.1155/2022/8547563

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Copyright © 2022 Dan Zhu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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DNP was associated with significantly added expression of CX43 in the spinal cord dorsal horn of STZ-induced diabetic rats at 5 weeks of the disease, which could be inhibited by intraperitoneal AMD3100 and NAC. (a) Western blot and (c) confocal images showed the protein expression of CX43 in the spinal cord dorsal horn. (b) Quantitative analysis of CX43 comparing with β-tubulin in the spinal dorsal at 5 weeks. All the data are demonstrated to be means ± SD. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001, n = 6/group. C, F, I, and M were merged images A and B, D and E, G and H, and J and K, separately. (d) Semiquantification of CX43 immunofluorescence intensity. n = 6/group (original magnification: 200×, scale bar 20 μm).