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Pathways of sphingolipid metabolism. GCDase, galactosylceramidase; GlcCDase, glucosylceramidase; GCS, glucosylceramide; CerK, synthase ceramide kinase; CerS1-6, ceramide synthase; KDHR, 3-keto-sphinganine reductase; SPT, serine palmitoyltransferase; DES, dihydroceramide desaturase; CDase, ceramidases; CerS, ceramide synthases; SPHK1/2, sphingosine kinase 1/2; SGPP, S1P phosphatase; SMS, sphingomyelin synthase; SMase, sphingomyelinase.
