Table 7.
Parameter assignment for sensitivity analysis of the decision tree combined with the Markov model (in USD).
Parameter | Minimum value | Class-mid value 1 | Baseline value | Class-mid value 2 | Maximum value |
---|---|---|---|---|---|
Full vaccination coverage | 74% | 80% | 86% | 90.5% | 95% |
BCR | 2.42 | 3.25 | 4.61 | 6.40 | 9.85 |
Effective rate of protection | 69.29% | 83.05% | 96.8% | - | - |
BCR | 1.42 | 2.39 | 4.61 | - | - |
Cost of vaccination (USD) | 56.50 | 58.00 | 59.51 | 60.87 | 62.23 |
BCR | 4.63 | 4.62 | 4.61 | 4.61 | 4.60 |
Discount rate | 3% | 4% | 5% | 5.5% | 6% |
BCR | 4.76 | 4.69 | 4.61 | 4.57 | 4.52 |
Cost for health status in the Markov model (in USD) | |||||
Acute hepatitis B | 2,025.82 | 3,052.82 | 4,080.29 | 6,129.40 | 8,178.51 |
Chronic hepatitis B | 1,614.49 | 2,586.78 | 3,559.47 | 4,350.67 | 5,141.87 |
Compensated cirrhosis | 2,259.81 | 3,660.86 | 5,061.64 | 6,585.46 | 8,109.28 |
Decompensated cirrhosis | 4,136.02 | 5,764.36 | 7,392.23 | 10,876.52 | 14,360.82 |
Liver cancer |
1,880.60 | 6,141.27 | 1,0401.73 | 22,197.05 | 33,990.37 |
Severe hepatitis B | 4,001.43 | 7,816.90 | 1,1631.93 | 13,311.29 | 14,990.65 |
BCR | 4.23 | 4.49 | 4.61 | 4.69 | 4.75 |