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. 2022 Jul 5;13:3875. doi: 10.1038/s41467-022-31479-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — a Schematic illustration of the experimental procedure. Photographs (b) and wound area (c) of the infected wounds after treatment (n = 5 biologically independent samples; mean ± SD). d Colony numbers of bacteria in infected wounds at 12 d post-treatment (n = 5 biologically independent samples; mean ± SD). e Immunofluorescence images of F4/80 (yellow), CD206 (green), and CD80 (violet) in infected wounds at 4th d post-treatment. Scale bar is 200 μm. Percentage of CD80⁺ (f) and CD206⁺ (g) area in F4/80⁺ area calculated from immunofluorescence images (n = 10 biologically independent samples; mean ± SD). h H&E and Masson’s trichrome-stained images of infected tissues at 12 d post-treatment. Scale bar is 500 μm. Statistical significance was analyzed via one-way ANOVA with a Tukey post-hoc test. Source data are provided as a Source Data file.