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. 2022 Jul 5;5:663. doi: 10.1038/s42003-022-03506-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Heat map demonstrating the level of immune cell infiltration in patients with high and low GPR87 expression, with immune cell infiltration evaluated by TIMER and CIBERSORT algorithms. b Lollipop graph shows the correlation between GPR87 expression and immune cells. c GPR87 was analyzed in correlation with immune scores and stromal scores, and differences in immune scores and stromal scores were analyzed in patients with high and low expression of GPR87. The immune scores and stromal scores were calculated by the ESTIMATE algorithm. d Differential analysis of regulatory T cells, macrophages, neutrophils, and T helper 2 cells in patients with high and low expression of GPR87. e Analysis of differences in CD4+/CD8+ cell ratios between patients with high and low expression of GPR87.