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. 2022 Jul 5;13:3866. doi: 10.1038/s41467-022-31130-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A FOXP3 MFI, B frequency of GZMB+, C MFI of CTLA-4, D Frequency of Ki67+, E CD25 MFI, F frequency of PD-1+ in cynomolgus monkey Tregs following HSA-IL2m treatment (n = 4). G median fluorescence intensity of FOXP3, CTLA4, CD39, CD73 and GITR in murine Treg following HSA-IL2m treatment in C57BL/6 mice (n = 6). H Suppression of conventional T cells by regulatory T cells from control mice (HSA), HSA-IL2m, and in vitro differentiated Tregs (n = 3). Data are presented as mean ± s.e. (A–F) and mean ± s.d. G–H Source data are provided as a Source Data file.