Fig. 2. Driver mutations and copy number aberrations for each CTC and bulk sample for the three patients.

Mutations were called using the Strelka algorithm (dark green). Mutations that were not called by Strelka but were manually recovered after visual inspection with at least one read showing the alternative allele are shown in light green. The stricken cell had no read covering the H193L mutation. Copy numbers are relative to a normalized ploidy of 2.