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. 2022 Jul 5;8:79. doi: 10.1038/s41523-022-00445-7

Fig. 3. CTC mutation analysis.

Fig. 3

a Number of bulk mutations called in CTC samples in patients #1, #2 and #3, respectively. b Number of CTC shared mutations in patients #1, #2, and #3, respectively. These are mutations shared among at least 2 CTC samples but absent from the bulk. c Number of CTC private mutations present in only one CTC sample and absent in the bulk, in patients #1, #2 and #3, respectively. Mutations in bulk and CTCs were independently called using the Strelka algorithm. Black circles represent CTC samples. d Clustering of the CTCs based on the mutational pattern.