Table 2.

MRI measures in relapsing versus progressive multiple sclerosis cases.

	RRMS, n=45	PMS, n=19	P value
				Adj for age and sexe
Total cortical lesions a
Lesion number	15, 28 (0–168)	56, 91 (2–203)	0.004c	0.0024
Lesion volume (μL)	384, 907 (0–9888)	1268, 3298 (32–8918)	0.021c	0.14
Leukocortical lesions a
Lesion number	5, 12 (0–66)	27, 36 (1–49)	0.0008c	0.006
Lesion volume (μL)	102, 230 (0–2818)	553, 948 (11–1698)	0.003c	0.020
Intracortical lesions a
Lesion number	1, 2 (0–17)	3, 7 (0–10)	0.006c	0.10
Lesion volume (μL)	4, 8 (0–65)	9, 27 (0–71)	0.035c	0.18
Subpial lesions a
Lesion number	6, 16 (0–142)	19, 47 (0–159)	0.008c	0.043
Lesion volume (μL)	209, 719 (0–9660)	760, 1900 (0–8015)	0.033c	0.50
White matter lesion volume (ml) a	5.7, 8.8 (0.5–50.8)	15.6, 21.3 (1.6–63.1)	0.0006c	0.09
Brain volume b	1512 ± 98	1433 ± 69	0.003d	0.17
Gray matter volume b	820 ± 103	759 ± 81	0.029d	0.95
Cortical volume b	644 ± 82	594 ± 65	0.025d	0.96
White matter volume b	692 ± 68	673 ± 57	0.31d	0.05
Spinal cord lesion number a	4, 7 (0–16)	11, 7 (1–19)	0.0007c	<0.0001

^aMedian, interquartile range (range).

^bMean ± standard deviation.

^cMann–Whitney test.

^dT-test.

^eGeneralized linear model.