A. Flow cytometry analysis of the frequencies of various immune cells after 20 weeks of exposure to control air, light WPS, and heavy WPS in lungs of Gprc5a−/−;Lcn2−/− mice. B. Flow cytometry analysis of IL-17A expression in CD4+ T cells, CD8+ T cells and B cells after 20 weeks of exposure to control air, light WPS, and heavy WPS in lungs of Gprc5a−/−;Lcn2−/− mice. C. IL-17A ELISA of BALF obtained from Gprc5a−/−;Lcn2−/− cells after 20 weeks of exposure to control air, light WPS, and heavy WPS. Differences between two groups were statistically examined using the Student’s t-test. *, P < 0.05; **, P < 0.01; ***, P < 0.001.