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H&E staining and Masson's trichrome staining at 4 and 12 weeks postoperatively to visualize in vivo repair of critical bone defects in the different groups treated with composite scaffolds. (A–B) The yellow box represents the edge of the defect area and the green box represents the center of the defect area (yellow arrow: new bone tissues; green arrow: blood vessels). Scale bar: 500 μm or 100 μm.
