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Structural features of AMH and AMHR2. Diagram of the structure of mature AMH (A) and AMHR2 ECD (B). (C) Comparison of the binding modes of each ligand class to a type II receptor. (D) Mapping of PMDS mutations (83), indicated by red spheres, to the binary complex. (E) Sequence of AMH and AMHR2 annotated with secondary structure features and highlighted in red with the above PMDS mutations.
