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. 2022 Jun 22;12:904614. doi: 10.3389/fonc.2022.904614

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Copyright © 2022 Zhang, Zhu, Guan and Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Establishment and analysis of the NRG clusters. (A) The consensus matrix, delta area, and consensus CDF by cluster analysis based on NRGs. Two clusters would be best. (B) Kaplan–Meier survival curves of two NRG clusters (p < 0.001). (C) Principal component analysis of NRG clusters. (D) Heatmap of NRG clusters and clinical data of DLBCL patients. Data of lactate dehydrogenases (LDH) and cell of origin (COO) are missing. (E) KEGG pathway enrichment analysis between NRG clusters by GSVA. (F) Immune infiltration between NRG clusters by ssGSEA. *p < 0.05, **p < 0.01, ***p < 0.001.