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. 2022 Jun 22;12:904614. doi: 10.3389/fonc.2022.904614

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Copyright © 2022 Zhang, Zhu, Guan and Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction and estimate of nomogram. (A) The univariate (green) and multivariate (red) Cox regression analysis of clinical characteristics and risk score. (B) The nomogram integrating COO, age, LDH, and risk score for DLBCL patients. (C) The calibration curve of the nomogram at 1, 3, and 5 years, respectively. (D) ROC curve of the nomogram, risk score, COO+IPI, and IPI score. ROC curves of the nomogram, risk score, COO+IPI, and IPI score in the CHOP regimen group (E) and RCHOP regimen group (F). ES, extranodal sites; COO, cell of origin; LDH, lactate dehydrogenases; GCB, germinal center B-cell like; ULN, upper limit of normal.