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. 2022 Jun 22;12:904614. doi: 10.3389/fonc.2022.904614

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Copyright © 2022 Zhang, Zhu, Guan and Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of immune infiltration and genetic variants underlying the different risk groups. (A) The correlation intensity between DEGs and immune cells. (B) The relationship of immune cells in risk score. γ/δ T cell and Macrophage 1 were negatively correlated with risk score while NK resting cell and Macrophage 2 were positively correlated (p < 0.01). The CNV frequency of (C) high-risk and (D) low-risk groups. (E) The TMB between the low- and high-risk group (p = 0.00074). (F) The correlation of TMB and risk score (p = 0.0049). *p < 0.05, **p < 0.01, ***p < 0.001.