FIG. 3.

Schematic representation of the methyltransferase gene cluster in H. chloromethanicum CM2^T. Gene orientations and positions are shown. Genes shown by genetic analysis of M. chloromethanicum CM4^T to be involved in methyl chloride dehalogenation are indicated by black arrows. Genes indicated by shaded arrows are predicted to have functions needed in a likely complete chloromethane catabolism pathway. Other open reading frames are indicated by open arrows. pCAW1 is a 5-kb BamHI fragment, pCAW2 is a 5.1-kb HindIII fragment, and pCM1 is a 2-kb HindIII fragment.