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. 2022 Jun 22;13:822721. doi: 10.3389/fgene.2022.822721

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Copyright © 2022 Liu, Xiao, Chen, Lou and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of VEGFA and EZH2 as the most potential downstream target genes in the established DNMT3B-associated miRNA–mRNA network. Overall survival (A) and relapse-free survival (B) analyses for 10 genes of interest in breast cancer. (B) Prognostic values of VEGFA and EZH2 in breast cancer determined by the Kaplan–Meier plotter. DNMT3B expression was significantly positively correlated with the expression of VEGFA (C) or EZH2 (D) in breast cancer assessed by GEPIA.