Table 2.
Levels of metabolic disorders parameters.
| T2D (n = 41) | Hypothyroidism (n=41) | T2D+ Hypothyroidism (n=38) | EW (n = 31) | HS (n=22) | P | |
|---|---|---|---|---|---|---|
| Weight (kg) | 77.78 ± 19.19 | 74.05 ± 13.86 | 80.73 ± 15.20* | 78.90 ± 17.06 | 68.30 ± 8.44* | .003 |
| Height (m) | 1.65±0.08 | 1.60±0.06† | 1.62±0.09* | 1.65±0.07 | 1.69 ± 0.09*,† | .001 |
| BMI (kg/m2) | 28.28 ± 5.29‡ | 28.81 ±5.51† | 30.68±4.83* | 28.83±4.71§ | 23.73 ± 0.75*,†,‡,§ | .0001 |
| WC (cm) | 94.60±16.77 | 88.61 ±15.61 | 93.43±13.30 | 87.15±17.97 | 84.00±9.53 | .072 |
| SBP (mm Hg) | 133.55 ± 17.62‡,§,‖,†† | 120.94 ± 13.12§,†† | 130.36 ± 15.09*,¶ | 118.37 ± 8.85‖,¶ | 116.82±4.77*,‡ | .0001 |
| DBP (mm Hg) | 68.81 ±8.99 | 65.65±8.37 | 69.57±7.84 | 70.84±10.73 | 70.00±6.90 | .212 |
| FBG (mg/dL) | 131.16 ± 39.76‡,§,||,†† | 86.42 ± 10.49§,#,†† | 114.64 ± 34.84*,¶,# | 87.76±9.00‖,¶ | 84.00±6.65*,‡ | .0001 |
| HbA1c (%) | 7.68 ± 1.39‡,§,‖,†† | 5.17±0.25§,#,**,†† | 6.92 ± 1.03*,¶,# | 5.64 ± 0.38§,‖,¶,** | 5.25 ± 0.30*,‡,§ | .0001 |
| TSH (uUI/mL) | 1.93±0.70 | 2.04±1.72 | 2.24±1.65 | 2.38±1.09 | 1.82±0.59 | .304 |
| Free-T4 (ng/dL) | 1.28±0.27 | 2.34±2.40 | 1.81 ±2.04 | 1.64±1.11 | 1.51 ± 0.57 | .330 |
| Ca (mg/dL) | 8.82±0.78 | 9.07±0.72 | 8.95±0.51 | 9.13±0.43 | 9.11 ± 0.66 | .379 |
| 25-OHD (ng/mL) | 18.50±6.72‡ | 19.42±9.48† | 18.25±8.32* | 19.56±4.54§ | 37.25 ± 7.72*,†,‡,§ | .0001 |
One-way analysis of variance (ANOVA) test (significant P< .05).
25-OHD=25-OH vitamin D, BMI=body mass index, Ca=calcium, DBP=diastolic blood pressures, EW=excess weight, FBG=fasting blood glucose, free-T4=free thyroxine, HbA1c=glycosylated hemoglobin A1c, HS = healthy subjects, SBP=systolic blood pressure, T2D=type 2 diabetes, TSH = thyroid-stimulating hormone, WC=waist circumference.
Post-hoc analysis revealed significant difference between HS and T2D+ hypothyroidism.
Post-hoc analysis revealed significant difference between HS and hypothyroidism.
Post-hoc analysis revealed significant difference between HS and T2D.
Post-hoc analysis revealed significant difference between HS and EW.
Post-hoc analysis revealed significant difference between T2D and EW
Post-hoc analysis revealed significant difference between T2D+ hypothyroidism and EW.
Post-hoc analysis revealed significant difference between hypothyroidism and T2D+ hypothyroidism.
Post-hoc analysis revealed significant difference between hypothyroidism and EW.
Post-hoc analysis revealed significant difference between T2D and hypothyroidism.