. 2022 Jun 22;9:907580. doi: 10.3389/fvets.2022.907580

Table 2.

Effect of bovine lactoferrin on enzymes bioactivities and serum protein electrophoresis in benzene-induced hematotoxicity.

Groups	Parameters
	AST (U/L)	ALT (U/L)	ALP (U/L)	LDH (U/L)	Total protein (gm/dl)	Albumin (gm/dl)	α1-globulin (gm/dl)	α2- globulin (gm/dl)	β- globulin (gm/dl)	γ- globulin (gm/dl)
Corn oil	205.67 ± 9.29^c	121.33 ± 11.02^e	238.67 ± 22.59^d	2407.67 ± 97.21^bc	7.30 ± 0.46^bc	5.08 ± 0.45^bc	0.16 ± 0.01^abc	0.54 ± 0.04^ab	0.58 ± 0.04^ab	0.94 ± 0.04^b
L100	214.67 ± 14.15^c	115.00 ± 10.44^e	233.67 ± 25.66^d	2377.33 ± 65.58^bc	7.99 ± 0.17^a	5.66 ± 0.08^a	0.17 ± 0.03^bc	0.62 ± 0.04^a	0.60 ± 0.04^ab	0.96 ± 0.08^b
L200	195.00 ± 21.66^cd	127.00 ± 1.00^e	224.67 ± 50.66^d	2416.33 ± 250.51^bc	7.83 ± 0.32^ab	5.46 ± 0.24^ab	0.16 ± 0.03^abc	0.58 ± 0.02^ab	0.63 ± 0.03^a	1.04 ± 0.09^ab
L300	180.33 ± 15.82^d	114.67 ± 11.50^e	222.67 ± 32.04^d	2204.00 ± 143.27^c	7.81 ± 0.29^abc	5.43 ± 0.14^abc	0.14 ± 0.03^abc	0.57 ± 0.05^ab	0.57 ± 0.04^ab	1.08 ± 0.05^a
Bz	328.33 ± 1.53^a	277.33 ± 8.09^a	457.00 ± 31.43^a	2797.67 ± 155.05^a	5.83 ± 0.35^e	3.91 ± 0.26^e	0.12 ± 0.01^c	0.44 ± 0.04^c	0.55 ± 0.03^b	0.81 ± 0.06^c
Bz+L100	310.00 ± 3.00^a	195.33 ± 5.51^b	396.67 ± 21.39^b	2588.67 ± 54.20^ab	6.59 ± 0.19^d	4.47 ± 0.14^d	0.13 ± 0.00^b	0.51 ± 0.02^b	0.57 ± 0.04^ab	0.90 ± 0.02^bc
Bz+L200	281.33 ± 3.21^b	175.00 ± 11.14^c	380.00 ± 10.54^bc	2374.67 ± 219.14^bc	7.14 ± 0.37^cd	4.95 ± 0.27^c	0.14 ± 0.01^ab	0.52 ± 0.04^b	0.61 ± 0.03^ab	0.93 ± 0.04^bc
Bze+L300	269.67 ± 1.53^b	147.67 ± 12.50^d	340.33 ± 26.65^c	2346.00 ± 46.78^bc	7.50 ± 0.56^abc	5.08 ± 0.38^bc	0.15 ± 0.01^abc	0.57 ± 0.05^ab	0.60 ± 0.06^ab	1.00 ± 0.10^ab

Corn group, received corn oil and distilled water as the Bz and bLf vehicles; L100 group, received bLf (100 mg/kg BW); L200 group, received bLf (200 mg/kg BW); L300 group, received bLf (300 mg/kg BW); Bz group, injected with Bz at a dosage of 2 ml/kg BW; Bz+L100 group, received bLf (100 mg/ kg BW, 30 min before Bz treatment); Bz+L200 group, received bLf (200 mg/ kg BW, 30 min before Bz treatment), and Bz+L300 group, received bLf (300 mg/ kg BW, 30 min before Bz treatment). Data are expressed as means ± SD. Mean values in the same row bearing different superscript letters were significantly differ at (P < 0.05).