. 2022 Jun 22;9:907580. doi: 10.3389/fvets.2022.907580

Table 3.

Effect of bovine lactoferrin on erythropoietin and serum iron profile in benzene-induced hematotoxicity.

Groups	Parameters
	Erythropoietin ng/L	Serum ferritin pmol/L	Serum iron μmol/L	TIBC μmol/L
Corn oil	3.97 ± 0.15^c	26.23 ± 1.57^d	170.33 ± 2.52^c	357.67 ± 5.13^c
L100	4.36 ± 0.31^c	34.53 ± 2.35^c	180.33 ± 2.31^b	367.67 ± 2.52^bc
L200	4.50 ± 0.17^c	40.17 ± 2.20^b	192.67 ± 5.51^a	378.33 ± 5.03^ab
L300	4.93 ± 0.38^c	52.40 ± 3.70^a	196.00 ± 7.21^a	389.33 ± 5.03^a
Bz	11.18 ± 0.98^a	10.73 ± 1.23^f	92.67 ± 5.51^f	281.67 ± 7.77^e
Bz+L100	10.71 ± 0.79^a	16.10 ± 1.64^e	119.67 ± 4.51^e	310.00 ± 13.23^d
Bz+L200	8.55 ± 0.48^b	29.22 ± 3.40^d	134.00 ± 4.58^d	355.00 ± 8.66^c
Bze+L300	8.10 ± 0.35^b	43.03 ± 2.64^b	176.00 ± 6.56^bc	388.67 ± 2.52^a

Corn group, received corn oil and distilled water as the Bz and bLf vehicles; L100 group, received bLf (100 mg/kg BW); L200 group, received bLf (200 mg/kg BW); L300 group, received bLf (300 mg/kg BW); Bz group, injected with Bz at a dosage of 2 ml/kg BW; Bz+L100 group, received bLf (100 mg/ kg BW, 30 min before Bz treatment); Bz+L200 group, received bLf (200 mg/ kg BW, 30 min before Bz treatment), and Bz+L300 group, received bLf (300 mg/ kg BW, 30 min before Bz treatment). Data are expressed as means ± SD. Mean values in the same row bearing different superscript letters were significantly differ at (P < 0.05).