Table 3.
Predictor studies eligible for pooled analysis but excluded due to incongruent stratification of predictor.
| Predictor | Outcome | Studies Eligible for Inclusion in the Meta-Analysis | Sample Size | Stratification Category | HR (95%CI) | P-Value |
|---|---|---|---|---|---|---|
| Recipient MELD | Patient Survival (Overall) | Haldar (2019)16 McCabe (2020)17 |
N=2741 N=11782 |
MELD <11 MELD >11–14 vs. <11 MELD >14–18 vs. <11 MELD >18–23 vs. <11 MELD >23 vs. <11 N/A |
1 1.03 (0.66–1.62) 0.66 (0.44–1.06) 0.71 (0.47–1.15) 1.48 (1.04–2.3) 1 (1–1.01) |
REF NS NS NS <0.05 0.458 |
| Recipient BMI | Patient Survival (Overall) | Haldar (2019)16 Nagai (2019)14 |
N=2741 N=6344 |
BMI ≤18.5 vs. >25.0, ≤30.0 BMI >18.5, ≤25.0 vs. >25.0, ≤30.0 BMI >30, ≤35 vs. >25.0, ≤30.0 BMI >30, ≤35 vs. >25.0, ≤30.0 BMI >40 vs. >25.0, ≤30.0 BMI <18.5 vs. 18.5–24.9 BMI 25–29.9 vs. 18.5–24.9 BMI 30–34.9 vs. 18.5–24.9 BMI 35–39.9 vs. 18.5–24.9 BMI 40+ vs. 18.5–24.9 |
4.29 (1.01–18.21) 2.24 (1.27–3.96) 1.96 (1.16–3.32) 1.38 (0.95–2.01) 1.43 (0.93–2.18) 0.88 (0.38–2) 0.86 (0.7–1.04) 0.73 (0.6–0.89) 0.82 (0.66–1.01) 0.88 (0.69–1.13) |
<0.05 <0.06 NS NS <0.05 0.33 0.12 <0.001 0.06 0.76 |
| Recipient Age | Patient Survival (Overall) | Haldar (2019)16 McCabe (2020)17 |
N=2741 N=11782 |
Age ≤45 Age 46–55 vs. ≤45 Age 56–60 vs. ≤45’ Age 61–65 vs. ≤45 Age >65 vs. ≤45 Age 50–64 vs. <50 |
1 1.31 (0.87–1.98) 1.23 (0.81–1.87) 2.07 (1.39–3.08) 1.72 (1.1–2.71) 1.54 (1.29–1.84) |
REF NS NS <0.001 <0.05 <0.001 |