Fig. 2. HER2-specific-affibody imaging in the clinical trial. Notes: PET imaging of HER2-negative patients (A) and HER2-positive patient (B) with 18F-FDG (A1, B1) and 68Ga-ABY-025 (A2, B2); standard uptake value (SUV) is normalized to 10 for all images; darker colors indicate higher uptake. Specific uptake and high contrast image is shown with 68Ga-ABY-025 compared to 18F-FDG-PET image. Adapted from ref. 35. Abbreviations: HER2, human epidermal growth factor receptor 2; ABY, affibody; SUV, standard uptake value; PET, positron emission tomography; and FDG, fluorodeoxyglucose.
