A, Triple-positive breast carcinoma in pretreatment core biopsy showing mucinous and micropapillary features. B, Invasive carcinoma shows diffuse and strong nuclear staining with ER. C, Variable staining with PR. D, HER2 showed 3+ staining. E, Postneoadjuvant excision specimen showing a complete response in the breast, characterized by a tumor bed composed of mucin pools only. F, Residual carcinoma was identified in an axillary lymph node associated with fibrosis, indicative of partial response (hematoxylin-eosin, original magnifications ×20 [A], ×2 [E], and ×4 [F]); original magnification ×20 [B through D]). Abbreviations: ER, estrogen receptor; PR, progesterone receptor.