Fig. 6.
Deformative ability of RNA nanoparticles contributes to favorable biodistribution. (A) Biodistribution comparison of iron, gold, and RNA nanoparticles with IVIS images of tumors and organs, and the fluorescent quantification of tumor to organ (liver and kidney) ratio; (B) Gel image of urine samples at 0.5 hr post IV injection of dsRNA, 3WJ, and 4WJ RNA nanoparticles; (C) IVIS images of organs and tumors collected at 12 and 24 hr post IV injection of 10 nm and 20 nm RNA square nanoparticles. Adapted with permission from [25]. Copyright 2020 American Chemical Society.