| definition of tracheobronchial
region (BB) |
generation 0–8 |
(21) |
| definition
of bronchiolar
region (bb) |
generations 9–16 |
(21) |
| definition
of alveolar interstitial
region (AI) |
generations 17–23 |
(21) |
| functional
residual capacity |
3000 mL |
(25) |
| extra-thoracic volume |
45 mL |
(25) |
| BB epithelial surface area |
0.031 m2
|
derived from (21) |
| bb epithelial surface area |
0.43 m2
|
derived from (21) |
| AI epithelial
surface area |
54.7 m2
|
derived from (21) |
| BB epithelial lining fluid
(ELF) depth |
9.7 μm |
derived from volume/area |
| bb epithelial lining fluid
(ELF) depth |
4.0 μm |
derived from volume/area |
| AI epithelial lining fluid
(ELF) depth |
0.15 μm |
derived from volume/area |
| BB ELF volume |
0.3 mL |
(1) |
| bb ELF volume |
1.7 mL |
(1) |
| AI ELF volume |
8.0 mL |
(1) |
| mucociliary (MCC) rate constant
(KcBB) |
0.69 h–1, t1/2, BB = 1 h |
(24) |
| mucociliary (MCC) rate constant
(Kcbb) |
0.078 h–1, t1/2, bb = 9 h |
(24) |
