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. 2022 Apr 27;19(7):2203–2216. doi: 10.1021/acs.molpharmaceut.2c00040

Figure 6.

Figure 6

Scatter plots comparing AUCinf, Cmax, and Foral predictions of the back-calculated clearance scaling method using the PBPK module (x-axis) vs the HTPK module (y-axis). Blue solid line and shaded gray area represent the linear regression and its 95% confidence interval, respectively.