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. 2022 Jul;33(7):1411–1426. doi: 10.1681/ASN.2021101396

Table 3.

Morphologic descriptors with limited or unclear prognostic value that could be reported for completeness on the basis of current clinical practices

Renal Compartment Individual Descriptor or Category Suggested Metric
Overall assessment for disease category FSGS versus MCD FSGS or MCD or MCD-like
Histology Tubulointerstitial Interstitial edema Present/absent
Interstitial eosinophils Present/absent
Vascular Arteriosclerosis 0, none
1+, mild
2+, moderate
3+, severe
Arteriolar hyalinosis 0, none
1+, mild
2+, moderate
3+, severe
EM Glomerular Foot process effacement 0, 0%–10%
1+, 11%–25%
2+, 26%–50%
3+, 51%–75%
4+, >75%
Podocyte detachment with newly formed matrix Present/absent
Condensation of the actin-based cytoskeleton 0, 0 (none)
1+, ≤50% (focal)
2+, >50% (diffuse)
Electron densities/hyaline material Present/absent