Table 2.
Stability data of optimized Nanosponges (ACN2) (Mean ± SD, n = 3).
| Storage condition | Months | Particle size (nm ± SD) | Zeta-potential (mV ± SD) | Encapsulation efficiency (%) | %DR (at 24 h) |
|---|---|---|---|---|---|
| – | 0 | 366 ± 2.6 | −19.2 ± 2.5 | 79.3 ± 1.6 | 77.1 ± 2.6 |
| RT (25 ± 2 °C) | 1 | 364 ± 1.4 | −19.3 ± 1.9 | 77.5 ± 2.1 | 77.4 ± 2.3 |
| 3 | 367 ± 6.3 | −17.6 ± 3.1 | 76.1 ± 3.7 | 75.9 ± 2.9 | |
| FT (4 ± 2 °C) | 1 | 363 ± 7.6 | −18.8 ± 4.9 | 73.2 ± 1.9 | 72.5 ± 1.7 |
| 3 | 374 ± 8.1 | −16.7 ± 5.0 | 70.3 ± 1.5 | 71.2 ± 1.5 | |
| AT (60 ± 2 °C, 75% RH) | 1 | 384 ± 9.6 | −14.4 ± 2.3 | 66.7 ± 1.1 | 68.4 ± 2.0 |
| 3 | 391 ± 7.5 | −9.6 ± 1.7 | 61.4 ± 2.1 | 64.2 ± 1.2 |
RT = Room temperature; FT = Freezing temperature and AT = Accelerated temperature.