Exhibited the platelet aggregation parameters. a: PAF, b: ET-1, c: TBX2, d: TF, e: Fbg and f: PAl-1. Data were presented as mean ± SEM. Tested group rats compared I/R where *P < 0.05, **P < 0.01 and ***P < 0.001. Where I/R = Ischemia reperfusion, SM = Sinomenine, NC = Normal Control, PAF = Platelet activating factor, ET-1 = Endothelin, TBX2 = Thromboxane B2, TF = Tissue factor, Fbg = Plasma fibrinogen, PAI-1 = Plasminogen activator inhibitor 1.