Skip to main content
. 2022 Mar 29;30(6):750–763. doi: 10.1016/j.jsps.2022.03.016

Fig. 6.

Fig. 6

Effect of ASSE and metformin on (A) exploration time of two familiar objects (FO1 and FO2) during the training session, (B) exploration time of familiar (FO1) and novel (NO) objects during the test session, (C) discrimination index of STZ-nicotinamide-induced diabetic rats model using novel object recognition test. Treatment of metformin and ASSE significantly increased the exploration time of NO and DI performance of diabetic rats in the test session. The results are expressed by mean ± SEM (n = 6). One-way ANOVA [F(4,25) = 9.621, p < 0.001 for FO1 and F(4,25) = 7.932, p < 0.001 for FO2 during training session; F(4,25) = 2.378, p > 0.05 for FO1 and F(4,25) = 17.76, p < 0.001 for NO during test session; F(4,25) = 17.89, p < 0.001 for DI] followed by Tukey-Kramer multiple comparisons test for comparisons of within the groups. The student's unpaired ‘t’ test was used to compare of correspond to each group of exploration time. $p < 0.05 and $$$p < 0.001 as compared to the corresponding group; *p < 0.05, and ***p < 0.001 as compared to the control group; #p < 0.05, ##p < 0.01 and ###p < 0.001 as compared to diabetic -induced group.