Table 2.
Time-zero Biopsy IRI and Histological Findings in Postreperfusion Biopsy.
| No IRI 96 (34.3%) |
Mild IRI 65 (23.2%) |
Moderate IRI 101 (36.1%) |
Severe IRI 18 (6.4%) |
Total OLT (N = 280 | P Value | |
|---|---|---|---|---|---|---|
| Steatosis degree | ||||||
| None (0–5%) | 80 (76.3%) | 50 (80%) | 77 (76.2%) | 16 (88.9%) | 223 (79.6%) | 0.70 |
| Mild (6–33%) | 14 (14.6%) | 11 (16.9%) | 19 (18.8%) | 2 (11.1%) | 46 (16.4%) | |
| Moderate (33–66%) | 2 (2.1%) | 2 (3.1%) | 4 (3.7%) | 0 | 8 (2.8%) | |
| Severe (>66%) | 0 | 2 (3.1%) | 1 (1%) | 0 | 3 (1.1%) | |
| Portal fibrosis | 36 (37.5%) | 20 (30.8%) | 32 (31.7%) | 6 (33.3%) | 94 (33.6%) | 0.79 |
| Apoptosis | 26 (27.1%) | 12 (18.5%) | 31 (29.8%) | 6 (40%) | 75 (26.8%) | 0.24 |
| Congestion | 20 (20.8%) | 8 (12.3%) | 23 (22.1%) | 5 (33.3%) | 56 (20%) | 0.22 |
| Haemorrhage | 17 (17.7%) | 14 (21.5%) | 21 (20.8%) | 3 (16.7%) | 55 (19.6%) | 0.90 |
| Neutrophilia grade | 0.01 | |||||
| Mild | 77 (80.2%) | 45(69.2%) | 58 (57.4%) | 8 (44.4%) | 188 (67.1%) | |
| Moderate | 4 (4.2%) | 8 (12.3%) | 36 (35.6%) | 5 (27.8%) | 53 (18.9%) | |
| Severe | 0 | 0 | 2 (2%) | 5 (27.8%) | 7 (2.5%) | |
| Necrosis Grade | 0.01 | |||||
| Absence | 30 (31.3%) | 20 (30.8%) | 17 (16.8%) | 0 | 67 (23.9%) | |
| Focal | 66 (68.8%) | 45 (69.2%) | 70 (69.3%) | 6 (33.3%) | 186 (66.4%) | |
| Confluent | 0 | 0 | 14 (13.9%) | 12 (66.7%) | 27 (9.6%) |
IRI, Ischaemia/reperfusion injury; OLT, orthotopic liver transplantation.