Table 5.
Time-zero Biopsy Ischaemia/Reperfusion Injury and Graft Outcomes.
Total N = 280 |
No IRI N = 96 |
Mild N = 65 |
Moderate N = 101 |
Severe N = 18 |
P Value | |
---|---|---|---|---|---|---|
Early allograft dysfunction | 54 (19.3%) | 14 (14.6%) | 14 (21.5%) | 20 (19.8%) | 6 (33.3%) | 0.27 |
Primary nonfunction | 11 (3.9%) | 2 (2.1%) | 2 (3.1%) | 6 (5.8%) | 1 (6.7%) | 0.52 |
Initial good graft function | 176 (62.8%) | 63 (65.6%) | 39 (60%) | 68 (67.3%) | 6 (33.3%) | 0.04 |
Peak ALT during first 7 days | 831 (±800) | 604.6 (±368) | 850 (±712.9) | 1043 (±107.5) | 1308 (724.8) | 0.002 |
Retransplantation within 90 days | 8 (2.9%) | 3 (3.1%) | 1 (1.5%) | 2 (2.0%) | 2 (11.1%) | 0.16 |
ALT, alanine aminotransferase; IRI, Ischaemia/reperfusion injury.