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. 2022 Jan 24;12(4):1102–1113. doi: 10.1016/j.jceh.2022.01.006

Table 3.

Comparison of Tight Junction Protein Expression Using H Score in Duodenal Mucosa in Study Subjects.

Tight junction protein Group 1 Control (n = 20) Group 2 NAFLD (n = 34) Group 3 ALD (n = 28) P value Pairwise comparison
Group 1 vs. 2 Group 1 vs. 3 Group 2 vs. 3
Claudin-3 villus 6 (4–8) 2 (0–4) 3 (3–5) 0.15 0.098 0.16 0.32
Claudin-3 crypt 6 (4–8) 2 (0–3) 3 (2–4) 0.043 0.033 0.054 0.28
Zonulin-1 villus 11 (6–12) 5 (0–8) 8 (8–14) 0.043 0.051 0.94 0.026
Zonulin-1 crypt 3 (1–10) 2 (1–4) 5 (3–12) 0.4 0.48 0.51 0.2