Table 3.
Comparison of Tight Junction Protein Expression Using H Score in Duodenal Mucosa in Study Subjects.
| Tight junction protein | Group 1 Control (n = 20) | Group 2 NAFLD (n = 34) | Group 3 ALD (n = 28) | P value | Pairwise comparison |
||
|---|---|---|---|---|---|---|---|
| Group 1 vs. 2 | Group 1 vs. 3 | Group 2 vs. 3 | |||||
| Claudin-3 villus | 6 (4–8) | 2 (0–4) | 3 (3–5) | 0.15 | 0.098 | 0.16 | 0.32 |
| Claudin-3 crypt | 6 (4–8) | 2 (0–3) | 3 (2–4) | 0.043 | 0.033 | 0.054 | 0.28 |
| Zonulin-1 villus | 11 (6–12) | 5 (0–8) | 8 (8–14) | 0.043 | 0.051 | 0.94 | 0.026 |
| Zonulin-1 crypt | 3 (1–10) | 2 (1–4) | 5 (3–12) | 0.4 | 0.48 | 0.51 | 0.2 |