Table 1.
All patients (N=27,343) | Propensity score-matched patients (n=5124) | |||||
---|---|---|---|---|---|---|
LDLT (n=2566) | DBD LT (n=24777) | p- value |
LDLT* (n=2566) | DBD LT (n=2566) | p- value |
|
Donor: | ||||||
Age (years) | 36.0 (28.0, 45.0) | 44.0 (29.0, 56.0) | <0.001 | 36.0 (28.0, 45.0) | 33.0 (22.0, 48.0) | <0.001 |
BMI (kg/m2) | 26.2 (23.5, 28.7) | 27.0 (23.5, 31.3) | <0.001 | 26.2 (23.5, 28.7) | 26.1 (22.5, 30.6) | 0.120 |
Male gender | 1214 (47.3) | 14447 (58.3) | <0.001 | 1214 (47.3) | 1276 (49.7) | 0.083 |
Caucasian race | 2088 (81.4) | 15780 (63.7) | <0.001 | 2088 (81.4) | 2031 (79.2) | 0.050 |
Cold ischemia (hours)* | 1.5 (1.0, 2.1) | 4.7 (4.0, 5.4) | <0.001 | 1.5 (1.0, 2.1) | 4.7 (3.9, 5.5) | <0.001 |
Recipient: | ||||||
Age (years) | 56.0 (46.0, 63.0) | 58.0 (51.0, 63.0) | <0.001 | 56.0 (46.0, 63.0) | 56.0 (47.0, 63.0) | 0.850 |
Male gender | 1401 (54.6) | 16275 (65.7) | <0.001 | 1401 (54.6) | 1425 (55.5) | 0.500 |
Caucasian race | 2087 (81.3) | 17965 (72.5) | <0.001 | 2087 (81.3) | 2005 (78.1) | 0.004 |
BMI (kg/m2) | 26.3 (23.3, 30.0) | 28.1 (24.6, 32.3) | <0.001 | 26.3 (23.3, 30.0) | 26.0 (23.2, 29.9) | 0.440 |
Post-transplant LOS (days) | 10.0 (8.0, 16.0) | 9.0 (6.0, 15.0) | <0.001 | 10.0 (8.0, 16.5) | 8.0 (6.0, 12.0) | <0.001 |
Waiting list time (days) | 150.0 (78.0, 302.0) | 96.0 (18.0, 284.0) | <0.001 | 150.0 (78.0, 302.0) | 163.5 (48.0, 351.0) | 0.079 |
Diabetes | 607 (23.7) | 6627 (26.7) | <0.001 | 608 (23.7) | 621 (24.2) | 0.920 |
Serum creatinine (mg/dL) | 0.8 (0.7, 1.1) | 1.0 (0.8, 1.6) | <0.001 | 0.8 (0.7, 1.1) | 0.9 (0.7, 1.1) | <0.001 |
Serum total bilirubin (mg/dL) | 2.7 (1.4, 4.8) | 3.9 (1.7, 10.9) | <0.001 | 2.7 (1.4, 4.8) | 2.0 (1.0, 4.3) | <0.001 |
MELD score | 15.0 (11.0, 20.0) | 21.0 (13.0, 30.0) | <0.001 | 15.0 (11.0, 20.0) | 14.0 (1.0, 20.0) | 0.004 |
Life support requirement | 20 (0.8) | 1515 (6.1) | <0.001 | 20 (0.8) | 42 (1.6) | 0.005 |
ICU | 32 (1.2) | 2739 (11.1) | <0.001 | 32 (1.2) | 70 (2.7) | <0.001 |
Dialysis requirement | 16 (0.6) | 2374 (9.6) | <0.001 | 16 (0.6) | 40 (1.6) | 0.001 |
Ascites (mild or worse) | 1628 (63.4) | 18518 (74.7) | <0.001 | 1628 (63.4) | 1607 (62.6) | 0.540 |
Hepatic encephalopathy (grade 1 or worse) | 1285 (50.1) | 15565 (62.8) | <0.001 | 1285 (50.1) | 1306 (50.9) | 0.560 |
Portal vein thrombosis | 295 (11.5) | 3092 (12.5) | 0.150 | 295 (11.5) | 295 (11.5) | 0.280 |
HCC | 450 (17.5) | 8326 (33.6) | <0.001 | 450 (17.5) | 520 (20.3) | 0.013 |
Values are n (%) or median (interquartile range).
There are 10 propensity-score matched variables presented in italics in this table. In addition, recipients were also matched on transplant year and etiology of liver disease
BMI = body mass index; DBD = donation after brain death; LT = liver transplantation; ICU = intensive care unit; LDLT = living-donor liver transplantation; LOS = length of stay; MELD = model for end-stage liver disease.