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. 2022 Jun 8;24(2):502. doi: 10.3892/etm.2022.11430

Table I.

Association between SIRT6 expression and the clinicopathological features of 68 patients with pancreatic cancer.

  Expression level of SIRT6  
Clinicopathological characteristics All cases High (n=34) Low (n=34) P-value
Sex       0.467
     Male 35 19 16  
     Female 33 15 18  
Age, years       0.806
     <60 29 14 15  
     ≥60 39 20 19  
Tumor size, cm       0.086
     <2 29 18 11  
     ≥2 39 16 23  
Distant metastasis       0.002a
     Positive 33 10 23  
     Negative 35 24 11  
Histological grade       0.029b
     High/moderate   13 22  
     Low   21 12  
TNM stage       0.027b
     I/II   19 10  
     III/IV   15 24  

aP<0.01 and

bP<0.05 vs. high SIRT6 expression group. SIRT6, sirtuin 6.