Table I.
Expression level of SIRT6 | ||||
---|---|---|---|---|
Clinicopathological characteristics | All cases | High (n=34) | Low (n=34) | P-value |
Sex | 0.467 | |||
Male | 35 | 19 | 16 | |
Female | 33 | 15 | 18 | |
Age, years | 0.806 | |||
<60 | 29 | 14 | 15 | |
≥60 | 39 | 20 | 19 | |
Tumor size, cm | 0.086 | |||
<2 | 29 | 18 | 11 | |
≥2 | 39 | 16 | 23 | |
Distant metastasis | 0.002a | |||
Positive | 33 | 10 | 23 | |
Negative | 35 | 24 | 11 | |
Histological grade | 0.029b | |||
High/moderate | 13 | 22 | ||
Low | 21 | 12 | ||
TNM stage | 0.027b | |||
I/II | 19 | 10 | ||
III/IV | 15 | 24 |
aP<0.01 and
bP<0.05 vs. high SIRT6 expression group. SIRT6, sirtuin 6.