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. Author manuscript; available in PMC: 2023 May 10.
Published in final edited form as: Immunity. 2022 May 10;55(5):800–818. doi: 10.1016/j.immuni.2022.04.007

Figure 3. Detection of viruses by pattern recognition receptors.

Figure 3.

Virus-derived RNA and DNA can be recognized by toll-like receptors (TLRs) and cytosolic sensors, resulting in the secretion of pro-inflammatory cytokines and IFNs. Inflammasome activation results in cytokine maturation and secretion and inflammation-induced cell death. IFNs activate gene expression programs that are important for downstream anti-viral immunity.