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. 2022 Jul 6;12:11417. doi: 10.1038/s41598-022-14746-1

Table 1.

Characteristics of included studies (N = 12).

First author Outcome domains Description of study design and participants Country Pre- and post-COVID-19 dates of data collection N (%) females or women (F/W) and males or men (M/M) Mean (SD) participant age or age range (%) Use of sex or gender
Anxiety symptoms Depression symptoms General mental health Stress
Dong57 SCL-90-R First-year undergraduate students from a single university recruited online who completed two assessments (one prior to COVID-19 and one during) China

09/2019

pre-11/2020a

F/W: 3162–3,277 (75.5–77.4)

M/M: 923–1064 (22.6–24.5)

19 (1) Gender
Lim60 PROMIS Anxiety PROMIS Depression PSS Patients with systemic lupus erythematosus from the Georgians Organized Against Lupus cohort who complete annual surveys United States

NR/2018–2019

03–04/2020

F/W: 295 (93.4)

M/M: 21 (6.6)

47 (13) Sex
Magson56 SCAS-C SMFQ-C Adolescents aged 13–16 years who complete annual assessments as part of an ongoing longitudinal cohort that began 4 years prior Australia

NR/2019

05/2020

Girls: 126 (50.8)

Boys: 122 (49.2)

14 (1) Inconsistent
Megías-Robles53 PANAS-NA Community sample aged 19–67 years who completed two assessments (one prior to COVID-19 and one during) Spain

11/2019

04/2020

F/W: 67 (65.7)

M/M: 35 (34.3)

30 (13) Gender

Pierce49

Daly50

GHQ-12 National probability-based sample of adults aged ≥ 18 years who are part of the United Kingdom Household Longitudinal Study; an ongoing longitudinal study which has been collecting data continuously since 2009 United Kingdom Pre-COVID-19 wavesb

F/W: 7181c (46.7)

M/M: 8195c (53.3)

18–34 (11.5)d

35–49 (22.4)d

50–64 (34.5)d

65 + (31.6)d

Gender

Inconsistent

04–09/2020

F/W: 6380 (58.4)

M/M: 4538 (41.6)

Rimfeld54 GAD-7 SMFQ Adult twins born between 1994–1996 who, at age 18 months, were enrolled in the Twins Early Development Study; a longitudinal study which has collected over 14 waves of assessment in 20 years of data collection United Kingdom

NR/2018

04–05/2020

F/W: 2513–2578e (69.8–70.5)

M/M: 1050–1116e (29.5–30.2)

24–26 (100.0) Inconsistent
Saraswathi58 DASS-21 Anxiety DASS-21 Depression DASS-21 Stress Convenience sample of undergraduate university medical students who completed two assessments (one prior to COVID-19 and one during) India

12/2019

06/2020

F/W: 139 (64.1)

M/M: 78 (35.9)

20 (2) Inconsistent
Savage59 WEMWBS PSS Undergraduate students from a single university recruited by email invitation and completed three or more assessments as part of the Student Health Study, a longitudinal cohort study United Kingdom

10/2019

04/2020

F/W: 154 (72.0)

M/M: 60 (28.0)

18–21 (64.5)

22–25 (22.0)

26–35 (7.5)

35 + (6.1)

Inconsistent
Shanahan55 PSS Young adults who completed 9 assessments since 2004 as part of the Zurich Project on the Social Development from Childhood to Adulthood, a longitudinal cohort study Switzerland

NR/2018

04/2020

F/W: 378 (48.1)

M/M: 408 (51.9)

22 (0) Sex

van der Velden51

van der Velden52

MHI-5 National probability-based sample of adults aged ≥ 18 years who were enrolled and completed assessments for the Longitudinal Internet Studies for the Social Sciences since 2007 The Netherlands

03/2019

11–12/2019

03/2020

11–12/2020

F/W: 2020 (50.7)

M/M: 1963 (49.3)

F/W: 2062 (50.7)

M/M: 2002 (49.3)

18–34 (24.9)f

35–49 (22.9)f

50–64 (26.1)f

65 + (26.1)f

Gender

Sex

DASS-21 Anxiety = Depression, Anxiety, and Stress Scale—Anxiety subscale; DASS-21 Depression = Depression, Anxiety, and Stress Scale—Depression subscale; DASS-21 Stress = Depression, Anxiety, and Stress Scale—Stress subscale, GAD-7 Generalized Anxiety Disorder-7; GHQ-12 = General Health Questionnaire-12; MHI-5 = Mental Health Index-5; PANAS-NA = Positive and Negative Affect Schedule—Negative affect subscale; PROMIS Anxiety = Patient-Reported Outcomes Measurement Information System—Anxiety subscale; PROMIS Depression = Patient-Reported Outcomes Measurement Information System—Depression subscale; PSS = Perceived Stress Scale; SCAS-C = Spence Children's Anxiety Scale—Child; SCL-90-R = Symptom Check List-90 Revised; SMFQ = Short Mood and Feelings Questionnaire; SMFQ-C = Short Mood and Feelings Questionnaire—Child Version; WEMWBS = Warwick Edinburgh Mental Wellbeing Scale.

aAuthors did not provide dates of data collection. The article was identified in a November 9, 2020 search. bAnalyses compared COVID-19 symptom levels to preceding trends across multiple assessments. cNumber included in fixed effects regression analysis from where the majority of data were extracted. dAge groups reported for Daly48; for Pierce,49 16–24 = 8.8%, 25–34 = 11.2%, 35–44 = 16.0%, 45–54 = 20.1%, 55–69 = 28.9%, 70 + = 15.1%. eNumber of participants differed by outcome. fBased on van der Velden.51.