Table 2.

Outcome summary comparing EUS-CD to percutaneous transhepatic biliary drainage in the overall cohort (n=86) and in the subgroup of patients with malignant distal biliary obstruction (n=69)

Outcomes	Overall cohort (n=86)			Malignant distal biliary obstruction only (n=69)
	EUS-CD (n=28)	PTBD (n=58)	P	EUS-CD (n=23)	PTBD (n=46)	P
Technical success, n (%)	28 (100)	56 (96.6)	0.3	23 (100)	45 (97.8)	0.48
Clinical success, n (%)	22 (84.6)	36 (62.1)	0.04	17 (81)	32 (69.6)	0.33
Adverse events, n (%)	4 (14.3)	17 (29.3)	0.1	3 (13)	13 (28.3)	0.16
Occlusion	1 (3.6)	6 (10.3)	0.3	1 (4.3)	6 (13)	0.26
Cholangitis	3 (10.7)	7 (12.1)	0.85	2 (8.7)	5 (10.9)	0.78
Migration	0	4 (6.9)	0.16	0	4 (8.7)	0.15
Perforation	0	1 (1.7)	0.49	0	1 (2.2)	0.48
Bile leak	2 (7.1)	2 (3.5)	0.45	2 (8.7)	1 (2.2)	0.2
Bleeding	0	3 (5.2)	0.2	0	2 (4.4)	0.31
Need for reintervention, n (%)	3 (10.7)	45 (77.6)	<0.001	2 (8.7)	35 (76.1)	<0.001
Time for reintervention (days), mean±SD*	268 (315)	64 (261)	<0.001	357.5 (74.2)	74 (295)	<0.001
Number of reinterventions, mean±SD	0.14 (0.45)	1.9 (2.1)	<0.001	0.13 (0.45)	2 (2.3)	<0.001
Death, n (%)	16 (57.1)	47 (81)	0.02	15 (65.2)	45 (97.8)	<0.001

*Among patients with malignant obstruction. EUS-CD: EUS-guided choledochoduodenostomy; PTBD: Percutaneous transhepatic biliary drainage; SD: Standard deviation