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. 2022 Jul 6;14:92. doi: 10.1186/s13098-022-00861-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Associations of the longitudinal changes of SUA with incident MetS by different baseline SUA levels. a SUA longitudinal absolute changes in men. b SUA longitudinal percent changes in men. c SUA longitudinal absolute changes in women. d SUA longitudinal percent changes in women. HR hazard ratio, CI confidence interval. Baseline SUA group: men (< − 360 μmol/L, 360 to < 420 μmol/L, ≥ 420 μmol/L); women (< − 260 μmol/L, 260 to < 360 μmol/L, ≥ 360 μmol/L). Cut-off values of quintiles of SUA absolute changes: men (< − 32 μmol/L, − 32 to < − 6 μmol/L, − 6 to < 15 μmol/L, 15 to < 42 μmol/L, ≥ 42 μmol/L); women (< − 28 μmol/L, − 28 to < − 5 μmol/L, − 5 to < 14 μmol/L, 14 to < 37 μmol/L, ≥ 37 μmol/L). Cut-off values of quintiles of SUA percent changes: men (< − 8.39%, − 8.39% to < − 1.77%, − 1.77% to < 4.36%, 4.36% to < 12.14%, ≥ 12.14%); women (< − 10.19%, − 10.19% to < − 1.90%, − 1.90% to < 5.75%, 5.75% to < 15.29%, ≥ 15.29%). The analysis adjusted for baseline age (continuous, years), smoking status (yes and no), drinking status (yes and no), TC (mmol/L), LDL-C (mmol/L) and SCr (μmol/L)