Table 1.
The baseline characteristics of participants by different levels of baseline serum uric acid
| All (n = 44,176) | Quintile of baseline serum uric acid | P | |||||
|---|---|---|---|---|---|---|---|
| Q1 (n = 8655) | Q2 (n = 8831) | Q3 (n = 8954) | Q4 (n = 8812) | Q5 (n = 8924) | |||
| Age (year) | 37 (30, 47) | 36 (29, 44) | 37 (29, 46) | 37 (30, 48) | 38 (30, 48) | 38 (31, 48) | < 0.001 |
| Gender | < 0.001 | ||||||
| Men | 21,972 (49.7%) | 488 (2.2%) | 1579 (7.2%) | 4450 (20.2%) | 7006 (31.9%) | 8449 (38.5%) | |
| Women | 22,204 (50.3%) | 8167 (36.8%) | 7252 (32.7%) | 4504 (20.3%) | 1806 (8.1%) | 475 (2.1%) | |
| Smoking | < 0.001 | ||||||
| No | 36,643 (82.9%) | 8465 (23.1%) | 8272 (22.6%) | 7470 (20.4%) | 6442 (17.6%) | 5994 (16.3%) | |
| Yes | 7533 (17.1%) | 190 (2.5%) | 559 (7.4%) | 1484 (19.7%) | 2370 (31.5%) | 2930 (38.9%) | |
| Drinking | < 0.001 | ||||||
| No | 31,114 (70.4%) | 7983 (25.6%) | 7638 (24.5%) | 6449 (20.7%) | 4966 (16.1%) | 4078 (13.1%) | |
| Yes | 13,062 (29.6%) | 672 (5.1%) | 1193 (9.1%) | 2505 (19.2%) | 3846 (29.4%) | 4846 (37.2%) | |
| SBP (mmHg) | 116 (107, 124) | 111 (103, 119) | 112 (104, 121) | 116 (107, 124) | 118 (110, 127) | 119 (113, 128) | < 0.001 |
| DBP (mmHg) | 70 (63, 77) | 66 (61, 73) | 67 (61, 74) | 70 (63, 77) | 72 (66, 79) | 73 (67, 80) | < 0.001 |
| BMI (kg/m2) | 22.1 (20.3, 24.0) | 20.7 (19.3, 22.2) | 21.2 (19.6, 22.9) | 22 (20.3, 23.7) | 22.9 (21.1, 24.5) | 23.8 (22.1, 25.2) | < 0.001 |
| TG (mmol/L) | 1.04 (0.76, 1.44) | 0.82 (0.64, 1.09) | 0.89 (0.69, 1.19) | 1.04 (0.78, 1.41) | 1.17 (0.87, 1.57) | 1.37 (1.02, 1.86) | < 0.001 |
| HDL-C (mmol/L) | 1.39 (1.19, 1.62) | 1.55 (1.35, 1.77) | 1.5 (1.30, 1.73) | 1.39 (1.20, 1.61) | 1.3 (1.13, 1.50) | 1.22 (1.08, 1.41) | < 0.001 |
| LDL-C (mmol/L) | 2.65 (2.24, 3.15) | 2.43 (2.04, 2.89) | 2.56 (2.14, 3.01) | 2.67 (2.26, 3.15) | 2.78 (2.37, 3.26) | 2.87 (2.48, 3.36) | < 0.001 |
| TC (mmol/L) | 4.73 (4.20, 5.31) | 4.56 (4.05, 5.14) | 4.67 (4.14, 5.23) | 4.74 (4.22, 5.31) | 4.81 (4.27, 5.36) | 4.86 (4.35, 5.47) | < 0.001 |
| FBG (mmol/L) | 4.94 (4.68, 5.23) | 4.93 (4.68, 5.19) | 4.92 (4.67, 5.20) | 4.94 (4.67, 5.23) | 4.97 (4.70, 5.26) | 4.96 (4.69, 5.24) | < 0.001 |
| SUA (μmol/L) | 308 (255, 368) | 219 (200, 232) | 265 (254, 275) | 307 (296, 317) | 353 (341, 367) | 420 (398, 450) | < 0.001 |
| SCr (μmol/L) | 63 (53, 75) | 52 (47, 57) | 55 (50, 62) | 63 (55, 73) | 72 (63, 79) | 76 (69, 82) | < 0.001 |
Data are presented as median (interquartile range) values for continuous variables, percentage form (%) for categorical variables
MetS metabolic syndrome, DBP diastolic blood pressure, SBP systolic blood pressure, BMI body mass index, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, FBG fasting blood glucose, SUA serum uric acid, SCr serum creatinine
P values were calculated using analysis of Kruskal–Wallis test and Chi-square test for continuous and categorical variables, respectively