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. 2022 Jul 6;20:317. doi: 10.1186/s12951-022-01496-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Anti-viral effect of CME and GME on DENV infected megakaryocyte. A Immunoblot showing NS3 expression in DENV-2 infected megakaryocytes treated with two different concentrations of GME and CME for 48 hpi. B Bar graph showing densitometry analysis of NS3 protein expression from four independent experiments. C Histogram FACS plots showing DENV-2 infection in megakaryocytes. D Bar graph representing the percentage of normalized DENV-2 infection upon treatment with GME and HiGME in DENV-2 infected megakaryocytes. Data is mean ± SD from three independent experiments