Table 1.

Baseline characteristics

Baseline characteristics	Aspergillus fumigatus	No persistent Aspergillus fumigatus	p-value
	n (%)	n (%)
Total	64 (15)	373 (85)
Demographics and CF characteristics
Age, years (mean ± SD)	21.5 ± 12.8	23.9 ± 13.4	0.18
Female sex	30 (47)	178 (48)	0.90
Homozygous DeltaF508	35 (55)	161 (43)	0.09
CF-related diabetes	15 (23)	62 (17)	0.19
Pancreatic insufficiency	61 (95)	320 (86)	0.035
Microorganisms
Chronic PsA colonization	17 (28)	155 (42)	0.040
Treatments
Inhaled antibiotics	33 (54)	118 (33)	0.001
Inhaled corticosteroids	15 (23)	122 (33)	0.12
Macrolides	12 (19)	136 (37)	0.005
Inhaled rhDNase	22 (34)	107 (29)	0.38
Lung function and other clinical parameters
ppFEV1 (mean ± SD)	81.2 ± 21.9	79.1 ± 22.7	0.50
ppFVC (mean ± SD)	94.7 ± 16.1	93.5 ± 17.1	0.59
Number of IV-antibiotics (median (IQR))	1 (0–2)	1 (0–3)	0.66
Hospitalization days (median (IQR))	0 (0–2)	0 (0–0)	0.081
Total IgE (median (IQR))a	40.0 (10.5–77.0)	41.5 (16.5–120.0)	0.39
Eosinophils (median (IQR))b	0.3 (0.1–0.4)	0.2 (0.1–0.3)	0.086

Patients who developed colonization with A. fumigatus compared to those who remained aspergillus-free

IQR Interquartile Range; PsA Pseudomonas aeruginosa; ppFEV1 percent predicted Forced Expiratory Volume in one second; ppFVC percent predicted Forced Vital Capacity

Bold text indicating p-value < 0.05

^an = 273

^bn = 294