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. 2022 Jul 5;22:263. doi: 10.1186/s12890-022-02054-3

Table 2.

Baseline characteristics

Baseline characteristics Asymptomatic with treatment Asymptomatic without treatment p-value
n (%) n (%)
Total 19 (45) 23 (55)
Demographics and CF characteristics
Age, years (median (IQR)) 19.2 (11.4–33.5) 20.2 (12.7–29.1) 0.86
Female sex 7 (37) 9 (39) 0.88
Homozygous DeltaF508 8 (42) 14 (61) 0.23
CF-related diabetes 7 (37) 6 (26) 0.45
Pancreatic insufficiency 19 (100) 21 (91) 0.49
CF centre 0.00
 Gothenburg (n = 14) 0 14
 Lund (n = 11) 9 2
 Stockholm (n = 15) 10 5
 Uppsala (n = 2) 0 2
Microorganisms
Chronic PsA colonization 8 (42) 3 (15) 0.06
Treatments
Inhaled antibiotics 9 (50) 12 (54) 0.78
Inhaled corticosteroids 2 (11) 8 (35) 0.08
Macrolides 5 (26) 3 (13) 0.43
Inhaled rhDNase 7 (37) 5 (22) 0.28
Lung function and other clinical parameters
ppFEV1 (mean ± SD) 76.1 ± 22.6 82.0 ± 24.3 0.45
ppFVC (median (IQR)) 100.0 (79.2–104.7) 94.7 (86.5–107.2) 0.67
Number of IV-antibiotics (median (IQR)) 1 (0–3) 1 (0–3.25) 0.84
Hospitalization days (median (IQR)) 0 (0–3.5) 0 (0–2.25) 0.88
Total IgE (median (IQR))a 18.0 (9.1–88.5) 41.0 (10.7–55.3) 0.73
Eosinophils (median (IQR))b 0.2 (0.1–0.4) 0.2 (0.1–0.3) 0.58

Treated vs non-treated patients with asymptomatic A. fumigatus colonization

IQR Interquartile Range; PsA Pseudomonas aeruginosa. ppFEV1 percent predicted Forced Expiratory Volume in one second; ppFVC percent predicted Forced Vital Capacity

an = 25

bn = 26